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The Users' Guides to the Medical Literature is a series of articles originally published in the Journal of the American Medical Association, later rewritten This Users' Guide to the Medical Literature describes the fundamental concepts of platform trials and master protocols and reviews issues in the conduct and Practical focus and organization to guide clinicians through the fundamentals of using the medical literature to the more advanced strategies and skills for use Read Users' Guides to the Medical Literature: A Manual for Evidence-Based Clinical Practice, 3rd ed online now, exclusively on JAMAevidence. Founded around the Users' Guides to the Medical Literature,. Te Rational Clinical Examination: Evidence-Based Clinical. Diagnosis, and Care at the Close ofbook.1 This second edition of Users' Guides to the Medical Literature reflects that history and the evolving conceptual and pedagogic basis.