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You get drunk: You can drink alcohol when on zithromax but do it in moderation. If you have a significant infection i would advise abstaining until it hasDon't drink alcohol before, during, or up to three days after taking these drugs. Griseofulvin. Drinking alcohol while taking this medication can cause:. Azithromycin is generally a safe drug on its own. There are no serious dangers associated with drinking alcohol while taking this medication. However, if you