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A "microtome" is a specialized cutting tool used to cut extremely thin slices of tissue samples. When conducting the microtomy procedure, it is vital to Request PDF | Tissue Microtomy: Principle and Procedure | This chapter presents the technique of tissue sectioning for histopathological examination. This booklet has been prepared as a training aid for newcomers to microtomy and paraffin section preparation and as a refresher course for more experienced Microtomy is a method for the preparation of thin sections for materials such PRINCIPLE: microtome is a sectioning instrument that allows the cutting ofA microtome is a device that cuts extremely thin sections of tissue for microscopic study. They can be operated manually, semi-automatically or So the word “microtomy” means to cut the tissue in thin sections. For successful micro- scopic examination, it is necessary to have thin sections of the tissue