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If no there is no obvious threshold, use Youden's Index to establish the manual/roc.php 5 January 2009 Pallant J 2007 SPSS Survival Manual, 2nd Edition.ROC curve analysis in MedCalc includes calculation of area under the curve (AUC), Youden index, optimal criterion and predictive values. Calculation may be set to manual (on the Options command in Tools menu). Some indices, such as Youden's index have been included principally to allow I have calculated the ROC curve and its coordinates using SPSS, I can choose the maximum cutoff by eye balling but want to use Youden's index (Y.I) to