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Content of the WHO Malaria SME Reference Manual. 1. The two manuals have been combined into a single document and their content has been updated. This manual advises national malaria control programmes on the best methods to ensure access to early diagnosis and appropriate, effective case management Recognizing and promptly treating patients with severe malaria is essential. This handbook provides practical guidance on the diagnosis and clinical management This manual will guide them to search for the remaining malaria parasites in the community. Page 9. National Malaria Control and Elimination Program Manual ofThe aim of this interagency manual is to provide policy, strategy, technical and operational guidance to countries wishing to strengthen or set up routine