Dissolution is very crucial as it is the rate limiting factor. Types of dissolution apparatus pdf: Type 1 Basket apparatus 50-120rpm Conventional tablets, chewable tablets, CR Type 2 Paddle apparatus 25-50rpm orally Disintegrating tablets, chewable tablets, CR, suspensions Type 3 Reciprocating cylinder 6-35rpm CR, chewable tablets Follow the procedure for 10, 15 and 20 minutes as above. Calibration of Heater: 22.3.4.1.Set the temperature of the water in the beaker at 37°C. 22.3.4.2.Set the temperature of the water bath at 37°C. 22.3.4.3.Set the timer at 60 minutes. 22.3.4.4.Start the apparatus using `Start / Stop' key. PDF | Details on dissolution Apparatus. | Find, read and cite all the research you need on ResearchGate (SIF) pH-6.8 for subsequent 10 hours by USP-I dissolution apparatus, in 900 ml at 37.5± We developed our standard operating procedure (SOP) for the qualification of dissolution apparatus used for QC testing based on a risk analysis. The concept of this SOP is an enhanced mechanical qualification in line with phar-macopeial requirements. This SOP contains specifications that, in some cases, may be more stringent than USP or EP Procedure : Operation a) Ensure that clean purified water is filled in glass beakers at desired level.of DT machine b)Switch on the main supply on the instrument ON/OFF switch. c) Switch On the heater by pressing the "Temp" key on the panel. d) Press "Set" & Temp" key to set the temperature to 37 o C.