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Arterial Studies. The measurement of systolic blood pressure in the ankle is the most sensitive method of detecting large-vessel disease. The ankle–brachialBP is an important guide to cardiovascular risk and provides vital information on the haemodynamic condition of acutely ill or injured patients. BP constantly Methods For Obtaining a BP : All blood pressure measurements are made with reference to the atmospheric pressure. 1. DIRECT – Direct intra-arterial measurement