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The subtle and asymptomatic clinical and radiological features of this type of lesion as seen in the present case may delay early diagnosis and poor treatment outcome. Introduction: Osteosarcoma is common primary malignancy of bone that arises from the mesenchymal cells. It is commonly seen in younger patients having average age of 15 years. Generally, it involves long bones with fastest osteosarcoma was made. Based on the report, segmental resection of the right body of the mandible was performed with wide surgical resection margins. The resected tumor specimen also ex-hibited similar histopathological findings consistent with the incisional biopsy report of osteosarcoma. Discussion Soft tissue growth involving the gingiva is the tumor for the mandible.1,3In general, jaw osteosar- coma affects males more commonly than females and with an average age of 33-36 years old. The tumor pres - ents in the jaw about one to two decades later than osteo- sarcoma of the long bones.5,8To our knowledge, the case we are presenting is a rare one in terms of involving a fe- Osteosarcoma of the mandible Ajay Prakash, et, al. Indian J Dent Adv 2012; 4(4): 998-1001. 1000 b. Lymphoma - like pattern resembling large cell lymphoma showing large cells with abundant cytoplasm, round to oval nuclei, finely dispersed chromatin and prominent nucleoli; A case with detailed radiographic assessment using intraoral radiograph, computed tomography (CT), 3-D CT, CT angiography techniques and histological evaluation of osteosarcoma of jaws is presented. Osteosarcoma (OS) is a malignant connective tissue tumor originating from bone and is the most common primary bone malignancy of long bones but seldom arises in jaw bones.