The VELscope Vx system is a natural tissue fluorescence direct visualization system to be used as an adjunctive tool for oral mucosal examination.PDF | Oral squamous cell carcinoma is the most common form of malignancy of Tissue Fluorescence Imaging (VELscope) for Quick Non-Invasive Diagnosis in This helps in quick and non-invasive diagnosis. Keywords: Oral cancer; VELscope; autofluorescence; premalignant lesions; malignancies; diagnosis; sensitivity; The VELscope is an extremely effective aid for discovering and defining the extent of a wide range of mucosal abnormalities, including oral cancer. Importantly, The VELscope can act as an aid to identify potential oral mucosal diseases including oral cancer; however, the following must be considered: • Every patient and Proper Use of the VELscope in Dentistry (PDF). Key Points. The VELscope can act as an aid to identify potential oral mucosal diseases, including oral cancer